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Livres
Articles (43)
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Physical activity and exercise as countermeasures to physical frailty and sarcopenia

Marzetti, Emanuele, Calvani, Riccardo, Tosato, Matteo, Cesari, Matteo, Di Bari, Mauro, Cherubini, Antonio, Broccatelli, Marianna, Savera, Giulia, D’Elia, Mariaelena, Pahor, Marco, Bernabei, Roberto, L

Journal:

Aging Clinical and Experimental Research

Année:

2017

Langue:

english

Fichier:

PDF, 581 KB

english, 2017

VALIDATION OF THE ITALIAN VERSION OF THE OMNI SCALE OF PERCEIVED EXERTION IN A SAMPLE OF ITALIAN-SPEAKING ADULTS 1

GUIDETTI, LAURA, BROCCATELLI, MARIANNA, BALDARI, CARLO, BUZZACHERA, COSME FRANKLIM, GOSS, FREDRIC L., UTTER, ALAN C., SGADARI, ANTONIO

Journal:

Perceptual and Motor Skills

Année:

2011

Langue:

english

Fichier:

PDF, 4.51 MB

english, 2011

BDDCS Class Prediction for New Molecular Entities

Broccatelli, Fabio, Cruciani, Gabriele, Benet, Leslie Z., Oprea, Tudor I.

Journal:

Molecular Pharmaceutics

Année:

2012

Langue:

english

Fichier:

PDF, 451 KB

english, 2012

1,4-Dihydropyridine Scaffold in Medicinal Chemistry, The Story so Far And Perspectives (Part 1): Action in Ion Channels and GPCRs

Ioan, P., Carosati, E., Micucci, M., Cruciani, G., Broccatelli, F., S. Zhorov, B., Chiarini, A., Budriesi, R.

Journal:

Current Medicinal Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 641 KB

english, 2011

Best of Both Worlds: On the Complementarity of Ligand-Based and Structure-Based Virtual Screening

Broccatelli, Fabio, Brown, Nathan

Journal:

Journal of Chemical Information and Modeling

Année:

2014

Langue:

english

Fichier:

PDF, 339 KB

english, 2014

In silico absorption, distribution, metabolism, excretion and pharmacokinetics (ADME-PK): utility and best practices – An industry perspective from the International Consortium for Innovation through Quality in Pharmaceutical Development

Lombardo, Franco, Desai, Prashant V., Arimoto, Rieko, Desino, Kelly E., Fischer, Holger, Keefer, Christopher E., Petersson, Carl, Winiwarter, Susanne, Broccatelli, Fabio

Journal:

Journal of Medicinal Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 1.90 MB

english, 2017

Validation Of The Omni-cycle Scale Of Perceived Exertion In The Elderly

Broccatelli, Marianna, Buzzachera, Cosme F., Guidetti, Laura, Sgadari, Antonio, Utter, Alan C., Goss, Fredric L., Baldari, Carlo

Journal:

Medicine & Science in Sports & Exercise

Année:

2010

Langue:

english

Fichier:

PDF, 58 KB

english, 2010

Hi-intensity Interval Training And Constant Load Training Induce Similar Muscle Force Changes In Patients With Type 2 Diabetes Mellitus

Marianna, Broccatelli, Sgadari, Antonio, De Bellonia, Simona, Bernabei, Roberto

Journal:

Medicine & Science in Sports & Exercise

Année:

2014

Langue:

english

Fichier:

PDF, 278 KB

english, 2014

Hi-intensity Interval Training Vs. Constant Load Training

Sgadari, Antonio, Broccatelli, Marianna, De Bellonia, Simona, Bernabei, Roberto

Journal:

Medicine & Science in Sports & Exercise

Année:

2014

Langue:

english

Fichier:

PDF, 280 KB

english, 2014

Comparison Between Vo2max And Vo2peak In Elderly Subjects

Sgadari, Antonio, Broccatelli, Marianna, Tosato, Matteo, Bernabei, Roberto

Journal:

Medicine & Science in Sports & Exercise

Année:

2010

Langue:

english

Fichier:

PDF, 54 KB

english, 2010

Why Decreasing Lipophilicity Alone Is Often Not a Reliable Strategy for Extending IV Half-life

Broccatelli, Fabio, Aliagas, Ignacio, Zheng, Hao

Journal:

ACS Medicinal Chemistry Letters

Année:

2018

Langue:

english

Fichier:

PDF, 895 KB

english, 2018

Measuring knowledge and experience in two mode temporal networks

Everett, Martin G., Broccatelli, Chiara, Borgatti, Stephen P., Koskinen, Johan

Journal:

Social Networks

Année:

2018

Langue:

english

Fichier:

PDF, 1.35 MB

english, 2018

Transporter-Mediated Efflux Influences CNS Side Effects: ABCB1, from Antitarget to Target

Fabio Broccatelli, Emanuele Carosati, Gabriele Cruciani, Tudor I. Oprea

Journal:

Molecular Informatics

Année:

2010

Langue:

english

Fichier:

PDF, 831 KB

english, 2010

A Novel Approach for Predicting P-Glycoprotein (ABCB1) Inhibition Using Molecular Interaction Fields

Carosati, Emanuele, Neri, Annalisa, Frosini, Maria, Goracci, Laura, Oprea, Tudor I., Cruciani, Gabriele, Broccatelli, Fabio

Journal:

Journal of Medicinal Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 1.04 MB

english, 2011

BDDCS Applied to Over 900 Drugs

Leslie Z. Benet, Fabio Broccatelli, Tudor I. Oprea

Journal:

The AAPS Journal

Année:

2011

Langue:

english

Fichier:

PDF, 546 KB

english, 2011

Improving the prediction of the brain disposition for orally administered drugs using BDDCS

Fabio Broccatelli, Caroline A. Larregieu, Gabriele Cruciani, Tudor I. Oprea, Leslie Z. Benet

Journal:

Advanced Drug Delivery Reviews

Année:

2012

Langue:

english

Fichier:

PDF, 1.35 MB

english, 2012

QSAR Modeling and Data Mining Link Torsades de Pointes Risk to the Interplay of Extent of Metabolism, Active Transport, and hERG Liability

Broccatelli, Fabio, Mannhold, Raimund, Moriconi, Alessio, Giuli, Sandra, Carosati, Emanuele

Journal:

Molecular Pharmaceutics

Année:

2012

Langue:

english

Fichier:

PDF, 532 KB

english, 2012

QSAR Models for P-Glycoprotein Transport Based on a Highly Consistent Data Set

Broccatelli, Fabio

Journal:

Journal of Chemical Information and Modeling

Année:

2012

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2012

Predicting when Biliary Excretion of Parent Drug is a Major Route of Elimination in Humans

C. M. Hosey, F. Broccatelli, L. Z. Benet

Journal:

The AAPS Journal

Année:

2014

Langue:

english

Fichier:

PDF, 509 KB

english, 2014

Ligand Promiscuity between the Efflux Pumps Human P-Glycoprotein and S. aureus NorA

Brincat, Jean Pierre, Broccatelli, Fabio, Sabatini, Stefano, Frosini, Maria, Neri, Annalisa, Kaatz, Glenn W., Cruciani, Gabriele, Carosati, Emanuele

Journal:

ACS Medicinal Chemistry Letters

Année:

2012

Langue:

english

Fichier:

PDF, 685 KB

english, 2012

1,4-Dihydropyridine Scaffold in Medicinal Chemistry, The Story So Far And Perspectives (Part 2): Action in Other Targets and Antitargets

Carosati, E., Ioan, P., Micucci, M., Broccatelli, F., Cruciani, G., Zhorov, B.S., Chiarini, A., Budriesi, R.

Journal:

Current Medicinal Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 571 KB

english, 2012

Prevalence and risk factors associated with Clostridium difficile shedding in veal calves in Italy

Magistrali, Chiara Francesca, Maresca, Carmen, Cucco, Lucilla, Bano, Luca, Drigo, Ilenia, Filippini, Giovanni, Dettori, Annalisa, Broccatelli, Sayra, Pezzotti, Giovanni

Journal:

Anaerobe

Année:

2015

Langue:

english

Fichier:

PDF, 272 KB

english, 2015

Temporal dynamics in covert networks

Broccatelli, C., Everett, M., Koskinen, J.

Journal:

Methodological Innovations

Année:

2016

Langue:

english

Fichier:

PDF, 868 KB

english, 2016

Radiosensitization with low-dose carboplatin enhances pain palliation in radioisotope therapy with strontium-89

SCIUTO, R., MAINI, C. L., TOFANI, A., FIUMARA, C., SCELSA, M. G., BROCCATELLI, M.

Journal:

Nuclear Medicine Communications

Année:

1996

Fichier:

PDF, 417 KB

1996

Echocardiographic left ventricular hypertrophy in hypertension: marker for future events or mediator of events?

Verdecchia, Paolo, Angeli, Fabio, Achilli, Paola, Castellani, Claudia, Broccatelli, Andrea, Gattobigio, Roberto, Cavallini, Claudio

Journal:

Current Opinion in Cardiology

Année:

2007

Langue:

english

Fichier:

PDF, 262 KB

english, 2007

Factors Correlated with Rate of Perceived Exertion in Older Adults

Sgadari, Antonio, Broccatelli, Marianna, Rabini, Alessia, Bernabei, Roberto

Journal:

Medicine & Science in Sports & Exercise

Année:

2011

Langue:

english

Fichier:

PDF, 45 KB

english, 2011

Validation Of The Italian Version Of The Omni-cycle Scale Of Perceived Exertion In The Elderly

Broccatelli, Marianna, Sgadari, Antonio, Buzzachera, Cosme F., Guidetti, Laura, Utter, Alan C., Goss, Fredric L., Baldari, Carlo

Journal:

Medicine & Science in Sports & Exercise

Année:

2011

Langue:

english

Fichier:

PDF, 66 KB

english, 2011

Validation of the OMNI-Cycle Scale of Perceived Exertion in the Elderly

Guidetti, Laura, Sgadari, Antonio, Buzzachera, Cosme F., Broccatelli, Marianna, Utter, Alan C., Goss, Fredric L., Baldari, Carlo

Journal:

Journal of Aging and Physical Activity

Année:

2011

Langue:

english

Fichier:

PDF, 229 KB

english, 2011

Predicting passive permeability of drug-like molecules from chemical structure: where are we?

Broccatelli, F., Salphati, L., Plise, E., Cheong, J., Gobbi, A., Lee, M.-L., Aliagas, I.

Journal:

Molecular Pharmaceutics

Année:

2016

Langue:

english

Fichier:

PDF, 1.08 MB

english, 2016

Design, Synthesis, and Biological Evaluation of Pyrrolobenzodiazepine-containing Hypoxia-activated Prodrugs

Dragovich, Peter S., Broccatelli, Fabio, Chen, Jinhua, Fan, Peter, Le, Hoa, Mao, Weiguang, Pillow, Thomas H., Polson, Andrew G., Wai, John, Xu, Zijin, Yao, Hui, Zhang, Donglu

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2017

Langue:

english

Fichier:

PDF, 435 KB

english, 2017

Comparing Mechanistic and Preclinical Predictions of Volume of Distribution on a Large Set of Drugs

Chan, Rosa, De Bruyn, Tom, Wright, Matthew, Broccatelli, Fabio

Journal:

Pharmaceutical Research

Année:

2018

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2018

Comparing mechanistic and pre-clinical predictions of volume of distribution on a large set of drugs

Chang, Rosa, De Bruyn, Tom, Wright, Matthew, Broccatelli, Fabio

Journal:

Drug Metabolism and Pharmacokinetics

Année:

2018

Langue:

english

Fichier:

PDF, 48 KB

english, 2018

Computational Analysis of Kinase Inhibitor Selectivity using Structural Knowledge

Lo, Yu-Chen, Liu, Tianyun, Morrissey, Kari M, Kakiuchi-Kiyota, Satoko, Johnson, Adam R, Broccatelli, Fabio, Zhong, Yu, Joshi, Amita, Altman, Russ B, Valencia, Alfonso

Journal:

Bioinformatics

Année:

2018

Langue:

english

Fichier:

PDF, 964 KB

english, 2018

Evaluating the Utility of Canine Mdr1 Knockout Madin-Darby Canine Kidney I Cells in Permeability Screening and Efflux Substrate Determination

Chen, Eugene C, Broccatelli, Fabio, Plise, Emile, Chen, Buyun, Liu, Liling, cheong, jonathan, Zhang, Shu, Jorski, Jamie, Gaffney, Katherine, Umemoto, Kayla K, Salphati, Laurent

Journal:

Molecular Pharmaceutics

Année:

2018

Langue:

english

Fichier:

PDF, 1.09 MB

english, 2018

Strategies to optimize drug half-life in lead candidate identification

Broccatelli, Fabio, Hop, Marcel, Wright, Matthew

Journal:

Expert Opinion on Drug Discovery

Année:

2019

Fichier:

PDF, 1.58 MB

2019

Distribution of sexual health knowledge and attitudes in adolescent social networks: social network analysis of data from the STIs and Sexual Health feasibility study

McCann, Mark, Broccatelli, Chiara, Moore, Laurence, Mitchell, Kirstin

Journal:

Lancet (London, England)

Année:

2018

Fichier:

PDF, 54 KB

2018

Peer-led intervention to prevent and reduce STI transmission and improve sexual health in secondary schools (STASH): protocol for a feasibility study

Forsyth, Ross, Purcell, Carrie, Barry, Sarah, Simpson, Sharon, Hunter, Rachael, McDaid, Lisa, Elliot, Lawrie, Bailey, Julia, Wetherall, Kirsty, McCann, Mark, Broccatelli, Chiara, Moore, Laurence, Mitc

Journal:

Pilot and Feasibility Studies

Année:

2018

Langue:

english

Fichier:

PDF, 2.99 MB

english, 2018

Distribution of sexual health knowledge and attitudes in adolescent social networks: social network analysis of data from the STIs and Sexual Health feasibility study

McCann, Mark, Broccatelli, Chiara, Moore, Laurence, Mitchell, Kirstin

Journal:

Lancet (London, England)

Année:

2018

Langue:

english

Fichier:

PDF, 54 KB

english, 2018

Prediction of fraction unbound in microsomal and hepatocyte incubations – a comparison of methods across industry datasets

Winiwarter, Susanne, Chang, George, Desai, Prashant, Menzel, Karsten, Faller, Bernard, Arimoto, Rieko, Keefer, Christopher, Broccatelli, Fabio

Journal:

Molecular Pharmaceutics

Année:

2019

Langue:

english

Fichier:

PDF, 1021 KB

english, 2019

Correction to “Prediction of Fraction Unbound in Microsomal and Hepatocyte Incubations: A Comparison of Methods across Industry Datasets”

Winiwarter, Susanne, Chang, George, Desai, Prashant, Menzel, Karsten, Faller, Bernard, Arimoto, Rieko, Keefer, Christopher, Broccatelli, Fabio

Journal:

Molecular Pharmaceutics

Année:

2019

Fichier:

PDF, 182 KB

2019

Correction to “Prediction of Fraction Unbound in Microsomal and Hepatocyte Incubations: A Comparison of Methods across Industry Datasets”

Winiwarter, Susanne, Chang, George, Desai, Prashant, Menzel, Karsten, Faller, Bernard, Arimoto, Rieko, Keefer, Christopher, Broccatelli, Fabio

Journal:

Molecular Pharmaceutics

Année:

2019

Fichier:

PDF, 182 KB

2019

Advances in the study of drug metabolism â symposium report of the 12th Meeting of the International Society for the Study of Xenobiotics (ISSX)

Russell, Laura E., Schleiff, Mary Alexandra, Gonzalez, Eric, Bart, Aaron G., Broccatelli, Fabio, Hartman, Jessica H., Humphreys, W. Griffith, Lauschke, Volker M., Martin, Iain, Nwabufo, Chukwunonso, P

Journal:

Drug Metabolism Reviews

Année:

2020

Fichier:

PDF, 2.47 MB

2020

S6.3 - Application of in silico DMPK in drug discovery and development

Broccatelli, Fabio

Journal:

Drug Metabolism and Pharmacokinetics

Année:

2020

Fichier:

PDF, 43 KB

2020